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Research Library on Hydrogen Water Studies & Clinical Evidence

We curate and maintain a continuously updated collection of peer-reviewed studies, systematic reviews, and experimental research on hydrogen water and related wellness science. 

Each entry is for rapid scientific reference and evidence tracking.

Last Updated: August 2026

Hydrgeon Water Evidence Categories

More peer-reviewed studies are continuously being added as new research becomes available in biomedical journals and clinical trial registries.

Systematic Reviews & Meta-Analyses

1. Hydrogen Water: Extra Healthy or a Hoax? — A Systematic Review

📊 Systematic Review | 2024

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2. The Effects of Hydrogen-Rich Water … Metabolic Disorders Clinical Trials…

📊 Systematic Review & Meta-Analysis | 2024

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3.  The Effects of Hydrogen-Rich Water … in Clinical Populations…

📊 Systematic Review & Meta-Analysis | 2023

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4. The effect of hydrogen-rich water interventions…

📊 Systematic Review & Meta-Analysis | 2026

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5. Effects of Hydrogen-Rich Water and Pure Water on… 

📊 Systematic Review & Meta-Analysis | 2022

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6. The Impact of Hydrogen-Rich Water on Liver Enzyme Levels…

📊 Systematic Review & Meta-Analysis | 2024

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7. Can Molecular Hydrogen Supplementation ……..

 📊 Systematic Review & Meta-Analysis | 2024

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8. Effects of Molecular Hydrogen Supplementation…………

📊 Systematic Review & Meta-Analysis | 2023

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9. Can Molecular Hydrogen Supplementation Reduce ……

📊 Systematic Review & Meta-Analysis | 2024

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10. Anti-Inflammatory and Antioxidant Activity of …….

📊 Systematic Review & Meta-Analysis | 2024

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11. A Systematic Review of Molecular Hydrogen……

 📊 Systematic Review | 2023

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12. A Systematic Literature Review of the Effects…….

📊 Systematic Review | 2022

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13. Molecular Hydrogen Therapy — A Review on …..

📊 Review | 2023

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14. Molecular Hydrogen Therapy in Musculoskeletal…..

📊 Evidence-Based Review | 2026

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15. The Protective Role of Molecular Hydrogen ……

📊 Review | 2024

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16. Molecular Hydrogen for Outpatients with……

📊 RCT (Preprint) | 2024

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17. Hydrogen: An Advanced and Safest ……

📊 Review | 2025

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18. Prospects of Molecular Hydrogen in Cancer……..

📊 Review | 2024

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19. A Comprehensive Review of Molecular …….

📊 Review | 2025

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20. Exploring the Potential of Molecular Hydrogen………..

📊 Systematic Review | 2025

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21. The Effects of Hydrogen-Rich Water on…..

📊 Systematic Review | 2025

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22. Molecular Hydrogen Therapy for Neurological ……….

📊 Review | 2022

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23. Molecular Hydrogen and Kidney Diseases……..

📊 Scoping Review | 2026

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24. Molecular Hydrogen Is a Potential Protective …….

📊 Review | 2022

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25. Role and Mechanism of Molecular Hydrogen …..

📊 Review | 2025

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26. Clinical Use and Treatment Mechanism of …..

📊 Review | 2023

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27. Molecular Hydrogen Is a Promising Therapeutic…..

📊 Review | 2022

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To be continued…

Randomized Controlled Trials & Human Experimental Studies

1. Acute Effect of Hydrogen-rich Water on … 

📊 Research Article | 2023

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2. Hydrogen-rich Water Reduces … 

📊 RCT / Mechanistic Human Trial | 2020

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3. Hydrogen-Rich Water Reduces Liver…

📊 Randomized Controlled Pilot Trial | 2019

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4. Hydrogen-Rich Water Reduces Inflammatory Responses…

📊 Randomized Double-Blind Controlled Trial | 2020

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5. The Effects of 24-Week High-Concentration Hydrogen…

📊 Randomized Controlled Trial | 2020

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6. The Effects of 6-Month Hydrogen-Rich Water Intake…

📊 Randomized Controlled Pilot Trial | 2021

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7. Hydrogen-Rich Water Ameliorates Metabolic Disorder…

📊 Randomized Double-Blind Placebo-Controlled Clinical Trial | 2023

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8. Two-Week Continuous Supplementation of Hydrogen-Rich Water…

📊 Randomized Single-Blind Placebo-Controlled Trial | 2020

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9. Hydrogen-Rich Water Suppresses the Reduction in Blood…

📊 Randomized Crossover Trial | 2020

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10. Health Effects of Electrolyzed Hydrogen Water for the Metabolic…

📊 Randomized Controlled Trial | 2024

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11. Hydrogen-Rich Water Decreases Muscle Damage…

📊 Randomized, Double-Blinded, Placebo-Controlled Trial | 2025

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12. Effects of Hydrogen-Infused Water on Endurance…

 📊 Randomized-Controlled Clinical Trial | 2025

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13. Effects of Drinking Hydrogen-Rich Water…

📊 Randomized Controlled Pilot Trial | 2025

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14. The Effects of 8-Week Hydrogen-Rich Water…

📊 Randomized Controlled Trial | 2025

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15. Acute Ingestion of Hydrogen-Rich Water Does…

📊 Randomized, Double-Blind, Crossover Trial | 2020

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16. Short-Term Consumption of Hydrogen-Rich Water… 

📊 Randomized Pilot Study | 2022

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17. Hydrogen-Rich Water Consumption Positively Affects… 

📊 Randomized, Double-Blind, Placebo-Controlled Trial | 2021

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18. Effects of Hydrogen Water and Psychological…

 📊 Randomized and Controlled Clinical Trial | 2022

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19. The Effect of Hydrogen-Rich Water Consumption…

 📊 Randomized Controlled Trial | 2024

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20. Biological Effects of Hydrogen Water on Subjects with NAFLD…

📊 Randomized, Placebo-Controlled Trial | 2022

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21. Hydrogen-Rich Water and Caffeine for Alertness…

📊 Randomized-Controlled Cross-Over Trial | 2021

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22. Pilot Study of H2 Therapy in Parkinson’s Disease…

 📊 Randomized, Double-Blind, Placebo-Controlled Trial | 2013

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23. Randomized Double-Blind Placebo-Controlled Trial…

📊 Randomized, Double-Blind, Placebo-Controlled Trial | 2021

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24. Hydrogen Gas Inhalation Treatment in Acute Cerebral…

📊 Randomized Controlled Clinical Study | 2017

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25. The Effect of a Low Dose Hydrogen-Oxygen Mixture…

📊 Randomized, Placebo-Controlled Trial | 2022

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26. Hydrogen-Rich Water Decreases Serum LDL-Cholesterol…

📊 Clinical Trial | 2013

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27. Hydrogen-Rich Water Supplementation…….

📊 RCT / Clinical Trial | 2024

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28. Effects of 8 Days Intake of Hydrogen-Rich…..

📊 Clinical Trial | 2024

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29. Efficacy of Inhaled Hydrogen on Neurological …..

📊 Multi-Centre RCT | 2023

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30. Electrolyzed Hydrogen-Rich Water for Oxidative …..

📊 Multicenter RCT | 2022

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31. A Randomized, Placebo-Controlled Clinical…..

📊 Randomized Controlled Trial

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32. Long-Term Neuroprotective Effects of ……

📊 Preclinical Study | 2025

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33. Supplementation of Hydrogen-Rich Water……

📊 Randomized, Crossover Trial | 2008

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34. Therapeutic Efficacy of Infused Molecular Hydrogen……

📊 Randomized, Double-Blind, Placebo-Controlled Pilot Study | 2014

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35. Effect of Hydrogen-Rich Water on Oxidative …..

📊 Randomized Controlled Trial | 2013

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36. Effects of Drinking Hydrogen-Rich Water….

📊 Randomized, Placebo-Controlled Trial | 2011

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37. Open-Label Trial and Randomized, Double-Blind, ……

📊 RCT / Crossover Trial | 2011

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38. Positive Effects of Hydrogen-Water ….

📊 Parallel-Controlled Clinical Trial | 2018

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39. A Randomized Double-Blind Multi-Center ….

📊 Randomized, Double-Blind, Placebo-Controlled Multicenter Trial (Protocol) | 2016

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40. Hydrogen-Rich Water Consumption for ….

📊 Randomized, Double-Blinded, Placebo-Controlled, Parallel Trial (Protocol) | 2025

[View Study Findings]

41. The Effect of 14-Day Consumption of Hydrogen-Rich…..

📊 Randomized, Single-Blind, Placebo-Controlled Pilot Trial | 2024

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42. Effects of Natural Reduced (Hydrogen-Rich) ……

📊 Double-Blind Randomized Controlled Trial (Protocol) | 2021

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43. Clinical Observation of Hydrogen-Rich…..

📊 Randomized, Double-Blind, Controlled Clinical Trial | 2024

[View Study Findings]

To be continued…

Narrative & Mechanistic Reviews

1. Oral Administration of Hydrogen-rich Water…

📊 Literature Review | 2025

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2. Hydrogen-rich water as a modulator of gut microbiota?

📊 Narrative Scientific Review | 2021

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3. Health Benefits of Electrolyzed Hydrogen Water…

📊 Narrative Scientific Review | 2024

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4. Hydrogen-Rich Water to Enhance Exercise Performance…

📊 Narrative Review | 2024

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5. Molecular Hydrogen as a Novel Regulator …..

 📊 Mechanistic Review | 2025

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6. Clinical Use and Treatment Mechanism …..

📊 Narrative Review | 2023

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7. Molecular Hydrogen: Mechanism Against …..

📊 Narrative Review | 2025

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8. Delivery of Molecular Hydrogen for Precision …..

📊 Mechanistic Review | 2025

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9. Redox Mechanisms of Molecular Hydrogen ……

📊 Narrative Review | 2023

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10. Neuroprotective Effects of Molecular Hydrogen…..

📊 Critical Review | 2021

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11. Molecular Hydrogen and Post-Ischemic ….

📊 Narrative Review | 2022

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12. Mitochondria as a Hub for Molecular….

📊 Mechanistic Review | 2023

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13. Progress in the Application of Molecular …..

📊 Narrative Review | 2025

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14. Molecular Hydrogen Is a Promising ….

📊 Narrative Review | 2022

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15. Intermittent Environmental Exposure to….

📊 Experimental/Mechanistic Study | 2023

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16. Topically Applied Molecular Hydrogen ……

📊 Pilot Study | 2025

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17. Therapeutic Potential of Hydrogen-Rich….

📊 Mechanistic Study | 2024

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18. Using Oral Molecular Hydrogen Supplements….

📊 Pilot Observational Study | 2024

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19. Molecular Hydrogen Therapy…

📊 Narrative Review | 2023

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20. Hydrogen Therapy as a Potential Therapeutic…

📊 Narrative Review | 2023

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21. Effects of Molecular Hydrogen in the Pathophysiology…

📊 Mechanistic Review | 2024

[View Study Findings]

To be continued…

AptGadget Editorials on Hydrogen Water

Haftungsausschluss

This Research Library compiles and organizes publicly available scientific studies around hydrogen water for informational and educational reference. 

It does not constitute medical advice, and no claims are made regarding the efficacy or safety of any substance or intervention.